ABSTRACT
Background: Neonatal sepsis is a major cause of mortality and morbidity in newborn in developing countries. The spectrum of bacteria which causes neonatal sepsis varies in different parts of the world. Surveillance of causative organisms and their antibiotic sensitivity pattern promotes rational use of antibiotics and antibiotic stewardship. Objective: To assess the clinical and bacteriological profile of neonatal sepsis.Material & Methods:A retrospective study was conducted at Department of Pediatrics, Rajshahi Medical College Hospital, Rajshahi, Bangladesh from January to June 2019. Of the 207 neonates with clinical suspicion of sepsis, 55 neonates included. Culture positive sepsis was defined as isolation of bacterial pathogen from blood in neonates with clinical suspicion of sepsis.Results:Of the 207 neonates with clinical suspicion of sepsis, 55 neonates had blood culture positive sepsis. Sepsis was predominant in males (64.5%). Low birth weight (47.2%) and prematurity (40.9%) were important neonatal risk factors for sepsis. Early onset sepsis occurred in 58.1% of the cases and late onset sepsis in 41.9% of the neonates. Gram-positive cocci constituted 67.52% of all isolates and gram negative 30.76%. The most frequently isolated organism in blood was methicillin resistant coagulase negative staphylococcus (MRCONS) (32.47%). Gram positive organisms included MRCONS, methicillin resistant Staphylococci aureus (MRSA), group B Streptococci (GBS), Staphylococcus aureus and Enterococci. Among Gram-negative organisms, Acinetobacter was most frequently isolated followed by Klebsiella, Escherichia coli, Pseudomonas, Citrobacter and Burkholderia species. The mortality in the study group was 13.5%. Gram negative organisms were most resistant to ampicillin and cephalosporins. Gram positive isolates were least resistant to vancomycin and linezolid.Conclusion:In conclusion, gram positive sepsis was found to be common in present study, although mortality was high in gram negative sepsis. Careful measures have to be taken to overcome the change in trend of organisms causing sepsis, and selection of antibiotics should be prudent.
ABSTRACT
Hematidrosis is an extremely rare clinical entity characterized by recurrent episodes of skin bleeding mixed with sweat. We report a case of hematidrosis in a 10-year-old girl where detailed laboratory and histopathological investigation revealed no abnormality. The girl was successfully treated with propranolol with no recurrence of bleeding over a follow-up of 3 months.
ABSTRACT
Pancreaticogastrostomy is a less known operation for drainage. In this series pancreaticogastrostomy was done in 37 patients with dilated ducts during the period from 2002-2008. Anastomosis of the pancreas to the posterior wall of stomach was performed using pancreatic duct to gastric mucosa technique. The cases were followed up and it was seen that pancreaticogastrostomy is an effective operation for chronic pancreatitis. Most patients (89%) got relieved of pain for first several years. It is also a less time taking procedure to perform as no Roux-en-y construction is needed.
Subject(s)
Adult , Aged , Anastomosis, Surgical/adverse effects , Drainage/adverse effects , Female , Humans , Male , Middle Aged , Pain Measurement , Pancreatic Ducts/surgery , Pancreatitis, Chronic/diagnosis , Postoperative Complications , Quality of Life , Stomach/surgery , Treatment Outcome , Young AdultABSTRACT
In the present study 105 patients underwent appendicectomy by lateralised transverse cosmetic incision over a period from January, 2005 to September, 2007. Six patients developed complications like wound infection and fever. Wound infection was managed with antibiotics, postoperative pain with simple analgesics like tramadol hydrochloride and paracetamol. This cosmetic incision possesses maximum economic benefit. Even laparoscopic method takes more time, cost and skilled personnel.
Subject(s)
Adolescent , Adult , Appendectomy/methods , Appendicitis/surgery , Child , Cosmetic Techniques , Female , Follow-Up Studies , Humans , Length of Stay , Male , Middle Aged , Patient Satisfaction , Retrospective Studies , Treatment OutcomeABSTRACT
A random study for management of wound by cyanoacrylate glue in 213 patients, irrespective of age and sex with different types of wounds was carried out over a period of 4 years (1996-2000). In this series both dean surgical wounds and infected accidental wounds were included. Most of the patients recovered uneventfully, except 5, who showed wound gap. Reapplication of glue was done on them and 3 had similar wound union but 2 patients (0.94%) required surgical suture.